ECF Endorses the Radiologically Isolated Syndrome Consortium (RISC)
ECF is proud to announce its endorsement of the Radiologically Isolated Syndrome Consortium (RISC) and its work to advance research and collaboration in radiologically isolated syndrome.
The European Charcot Foundation (ECF) is pleased to support the Radiologically Isolated Syndrome Consortium (RISC), an international collaborative research network dedicated to advancing the understanding of radiologically isolated syndrome (RIS) and the presymptomatic phase of Multiple Sclerosis (MS).
Founded in 2009, RISC brings together researchers and organisations from across the international MS community to promote collaborative research, education and scientific initiatives focused on RIS and its progression towards clinically definite MS.
Advancing research in radiologically isolated syndrome
Through international, multicentre collaboration, RISC aims to strengthen the scientific foundation for the early identification and understanding of MS.
Its activities include improving risk stratification, supporting the refinement of diagnostic criteria for RIS, informing the design of prevention trials, and exploring emerging biomarkers and approaches to early intervention. RISC also includes the Pediatric RIS (PARIS) Consortium, which focuses on children with RIS and investigates genetic, environmental and serologic factors that may help predict future disease activity.
Since 2020, the RISC initiative has been supported by leading organisations and networks within the MS community, including SFSEP, FCRIN4MS, OFSEP, ECF, NMSS, IPMSSG, EAN, ECTRIMS, MENACTRIMS and ACTRIMS.
By fostering international collaboration and bringing together expertise from diverse multicentre cohorts, RISC contributes to advancing our understanding of the earliest stages of MS and to developing new approaches for early identification, monitoring and intervention.
Video with Prof. Christine LeBrun-Frenay: Understanding Radiologically Isolated Syndrome: here
Learn more about RISC: here
